Siv hd biography sample

Although the Berlin, London, and Düsseldorf adult patients appeared to have experienced a sterilizing human immunodeficiency virus (HIV) cure¹, the treatment regimen involved toxic chemotherapy followed by hematopoietic stem cell transplantation, which is not feasible for most patients due to the high risk and expense. In HIV-infected adult patients, proviral reservoirs are extremely stable during long-term antiretroviral therapy (ART), and become the driving force for viral rebound after analytic treatment interruption (ATI)^2,3,4,5,6. Although the timing of viral genome integration is uncertain in acute HIV infection, adult non-human primate models of simian immunodeficiency virus (SIV) suggest that proviral reservoirs are established as early as 3 days post infection^7,8. Mother-to-child HIV transmission can occur during in utero at late pregnancy, at the time of delivery or in the days or weeks after birth through breastfeeding^9,10. Current interventions to prevent in utero HIV infection have been highly successful, yet ~150,000 children are still postnatally infected with HIV every year¹¹. Although early initiation of ART in infants may red

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