Susumu tonegawa biography of christopher
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2021
- Christopher J. MacDonald, Susumu Tonegawa. Crucial role for CA2 inputs in the sequential organization of CA1 time cells supporting memory. Proceedings of the National Academy of Sciences (2021), 118 (3) e2020698118; DOI: 10.1073/pnas.2020698118
2020
- Bari, A., Xu, S., Pignatelli, M., Takeuchi, D., Feng, J., Li, Y., Tonegawa, S. Differential attentional control mechanisms by two distinct noradrenergic coeruleo-frontal cortical pathways. Proceedings of the National Academy of Sciences (2020); 202015635; DOI: 10.1073/pnas.2015635117
- Lak, A., Hueske, E., Hirokawa, J., Masset, P., Ott, T., Urai, A.E., Donner, T.H., Carandini, M., Tonegawa, S., Uchida, N., Kepecs, A. Reinforcement biases subsequent perceptual decisions when confidence is low, a widespread behavioral phenomenon. eLife (2020);9:e49834. DOI:10.7554/eLife.49834
- Sun, C., Yang, W., Martin, J., Tonegawa, S. Hippocampal neurons represent events as transferable units of experience. Nat Neurosci (2020). https://doi.org/10.1038/s41593-020-0614-x
- Josselyn, S. and Tonegawa, S. Memory engrams: recalling the past and imagining the future. Science 367: eaaw4325 (2020).
2019
- Zhang, X., Kim, J., Tonegawa, S. Amygdala Reward Neurons Form and Store Fear Extinction Memory, Ne
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Susumu Tonegawa
Japanese scientist (born 1939)
Susumu Tonegawa (利根川 進, Tonegawa Susumu, born September 5, 1939) is a Japanese scientist who was the sole recipient of the Nobel Prize for Physiology or Medicine in 1987 for his discovery of V(D)J recombination, the genetic mechanism which produces antibody diversity.[1] Although he won the Nobel Prize for his work in immunology, Tonegawa is a molecular biologist by training and he again changed fields following his Nobel Prize win; he now studies neuroscience, examining the molecular, cellular and neuronal basis of memory formation and retrieval.
Early life and education
[edit]Tonegawa was born in Nagoya, Japan and attended Hibiya High School in Tokyo.[2] While a student at Kyoto University, Tonegawa became fascinated with operon theory after reading papers by François Jacob and Jacques Monod, whom he credits in part for inspiring his interest in molecular biology.[3] Tonegawa graduated from Kyoto University in 1963 and, due to limited options for molecular biology study in Japan at the time, moved to the University of California, San Diego to do his doctorate study under Dr. Masaki Hayashi. He received his Ph.D. in 1968.
Career
[edit]Tonegawa conducted post-doctoral work at the Sal
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